New materials for freeform (FRESH) Bioprinting
FRESH bioprinting The beginning Bioprinting of soft materials such as hydrogels have long been impaired by their inability to hold its own form, rendering them "unprintable". Thankfully, in 2015, TJ Hinton and Adam Feinberg published a Science paper introducing the idea of FRESH bioprinting. The term "FRESH" stands for freeform reversible embedding of suspended hydrogels and herein they introduced the idea of using a thermo-reversible support bath to enable in situ bioprinting of complex 3D biological structures. The beauty of this technique lies in the freedom to print complex structures including overhangs while being supported by the temporary gel bath. This breakthrough innovation has truly enable researchers around the world to bioprint complex and intricate structures out of soft biological materials such as collagen, thus pulling off additive manufacturing of realistic tissue models like never before. This video demonstration shows the FRESH printing...